The defending Super Bowl champions roll into the Gateway City as the Giants battle the Rams in Week Two at the Edward Jones Dome. The G-Men opened their season at home with a 16-7 triumph over the NFC East-rival Redskins. Eli Manning ran one yard for a touchdown as New York raced out to a 16-0 lead in the first half and hung on from there. St. Louis is coming off a 38-3 drubbing at Philadelphia. Steven Jackson had just 40 yards on 14 carries for the Rams, who had just 166 total yards of offense to 522 for the Eagles. These teams last met in October of 2005 when the Giants won 44-24 at the Meadowlands.